Lepigen® for Control of Resistant Diamondback Moths (DBM)

An Effective and Economical Biological Insecticide without Harming Beneficial Insects

Lepigen® is a biological insecticide that controls Plutella xylostella (Diamondback Moth) larvae which are resistant to chemical insecticides.

Diamondback Moth melted on a cabbage leaf

Lepigen® is a Novel And Highly Selective Group 31 Mode of Action Insecticide for Resistant Diamondback Moth Control

Download the Tech Sheet
Plutella xylostella - Diamondback Moth
(A.I.): Autographa californica Multiple Nucleopolyhedrovirus
Suspension Concentrate (SC)
KEY CROPS with RATE of USE at 2.4floz/acre
  • Broccoli
  • Cabbage
  • Cauliflower
  • Kale
Diamondback Moth growth chart
Thorough crop coverage is essential, as the A.I. in Lepigen® must be ingested by larvae to be effective. Lepigen® is most effective when applied to small larvae at very early infestation levels.

Up to 3 days after application
Lepigen® effectively  targets very small DBM larvae (1st and 2nd instars). Infected small larvae feed very little, become increasingly lethargic, and are much more vulnerable to predation and environmental stress (i.e., dehydration).
4-6 days after application
At this stage, infected larvae are quite sick, stop feeding, and develop a dark brown color. Their skin bursts open, releasing billions of viral particles onto the environment. These viral particles are effectively dispersed by wind, rain, and predators and can infect other healthy DBM larvae.

Do not use Lepigen® as a curative treatment past the 3rd Instar (medium-small). In this situation, alternative control methods should be considered.
Lepigen® is compatible as a tank mix partner with insecticides*, fungicides and fertilizers. Ensure tank mixture solution pH is <8 prior to adding Lepigen® to the tank.
*Avoid mixing with B.T. Insecticide
Spray solution pH above 8 may damage the virus and reduce performance of Lepigen®. If needed, use a suitable buffer (acidifier).
Image of Heligen Gallon Container


Biological insecticide for the control of Plutella xylostella. larvae

Insect Target
Plutella xylostella (Diamondback Moth)

Registered Crops
Brassica leafy vegetables group, specifically cabbage, kale, cauliflower, and broccoli.

1 Gallon

Technical Information

Scout early! Be proactive with Lepigen® and get an economical lasting control.
Frequently Asked Questions
What is Lepigen®?
Lepigen® is a biological insecticide that controls Plutella xylostella (Diamondback Moth) larvae which are resistant to chemical insecticides.

What is the Active Ingredient in Lepigen®?
A Natural occurring virus called Autographa californica Multiple Nucleopolyhedrovirus

How Does Lepigen® Work?
Lepigen® is a suspension of virus particles called Occlusion Bodies (OB’s). When larvae ingest OB’s by eating Lepigen® sprayed crops, they become infected with the virus. Using the insect’s own metabolism, the virus replicates itself and invades almost every cell of the insect – causing them to rupture. This releases a virus-laden liquid, which spreads throughout the crop, providing ongoing control of susceptible caterpillars.

What Pests Does Heligen® Control?
Diamondback Moths. In other crops they can be referred to as...

Does Lepigen® Work on Larvae Populations that have Developed Resistance to Synthetic Insecticides?
Yes. It is a valuable rotational mixing partner in controlling larvae resistant to synthetic insecticides. There are no known cases of resistance developing to NPV-based insecticides anywhere in the world.

Is Lepigen® Harmful to Beneficials?
No, Lepigen® is a species-specific biological insecticide used to control Diamondback Moths and has no impact on beneficial species. Actually, beneficial species help transmit the virus throughout the ecosystem more quickly, which can result in better coverage and control.

What are the Approved Crops for Lepigen?
Crops include: Brassica leafy vegetables group, specifically cabbage, kale, cauliflower, and broccoli.

What is Lepigen’s PHI or REI?
Lepigen® does not have a pre-harvest interval (PHI). The re-entry interval (REI) is 4 hours.
How Much Does Lepigen® Cost?
Depending on the rate, about $...

What Should I Expect after Application?
Generally, Lepigen® will provide upwards of ...% control dependent upon environmental and weather conditions. Larvae may continue feeding for 1-3 days after becoming infected with NPV and will typically die within 3-9 days. Smaller larvae die faster, and warmer temperatures will increase the speed of kill. Expect slower results when temperatures are cooler (less than 65°F). NPV-infected larvae will not show obvious symptoms of disease until 1-2 days before death.

Is Lepigen® Compatible with Other Insecticides?
When mixed with water, Lepigen® is highly compatible with the majority of insecticides and fertilizers. Ensure that the mixture has a pH of 8 or less before adding Lepigen® as alkalinity will damage the virus. Avoid mixing with BT insecticides.

How Should Lepigen® be Stored?
Ideally, Lepigen® should be stored at temperatures below 34°F Do NOT leave in direct sunlight for longer than 2 hours or in spray tank for extended periods of time. Unused product can be stored in the original container for future use.

Does Lepigen® Have Any Residual Activity?
The virus in Lepigen® is degraded by ultraviolet light. As a result, the sprayed virus may only be viable for a few days in the crop. However, once the initial population dies, huge quantities of virus will be released. This replicated virus will last for many weeks and will control recurring populations. Applying the virus while larvae are most active (feeding) increases the likelihood of ingesting and ultimately higher levels of control.

How Do I Know If I Have Diamondback Moths in My Crop?
Look for...